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L-Carnosine (Carnosine)

L-Carnosine Dietary Supplement 500 mg Douglas Laboratories
Price Each: $27.80
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L-Carnosine - Amino Acid Dietary Supplement*

L- Carnosine is a naturally-occurring dipeptide normally found in brain and muscle. Discovered more than a century ago, carnosine has been shown to suppress the aged phenotype in cultured human cells. Carnosine seems to possess a number of protective functions including anti-oxidant, free-radical scavenger. Importantly, Carnosine can serves as a copper and zinc chelator and can suppress zinc and copper-induced neurotoxicity in neuron cells (1).

L-Carnosine is already a well-established anti-aging nutritional supplement that is used to support people with liver disease, cataracts, Alzheimer's disease, and cancer. Antonini and colleagues (2) showed that oral administration of L-carnosine to adult humans led to a rise in serum total anti-oxidant capacity. Recent studies have shown a tremendous potential of L-carnosine for improving language and behavior in children diagnosed with Autistic Spectrum Disorders (ASD). When autistic children were fed L-carnosine, their characteristic autistic behaviour was suppressed (3). Thus, the study indicates that L-carnosine supplementation can support healthy brain function.

L- Carnosine is considered an non-toxic and safe substance. As with other antioxidants, carnosine acts synergistically when taken with other antioxidants. (For example, when vitamin E was taken with carnosine, levels of both substances were higher in cardiac muscle than when either was taken alone.)

References:
1. Alan R. Hipkiss (2005) Could carnosine suppress zinc-mediated proteasome inhibition and neurodegeneration? Therapeutic potential of a non-toxic but non-patentable dipeptide. Biogerontology 6:147149
2. Antonini FM, Petruzzi E, Pinzani P, Orlando C, Poggesi M, Serio M, Pazzagli M and Masotti G (2002) The meat in the diet of aged subjects and the antioxidant effects of carnosine. Arch Gerontol Geriatr Suppl 8: 714
3. Chez MG, Buchanan CP and Aimonovitch MC (2002) Double-blind, placebo-controlled study of L-carnosine supplementation in children with autistic spectrum disorders. J Child Neurol 17: 833837
 
Suggested Usage: As a Dietary Supplement, take 1 capsule twice daily or as directed by a healthcare practitioner.
Ingredients: L-Carnosine
 Count: 30 Vegetarian Capsules
Net Weight per Capsule: 500 mg.
Servings Per Bottle: Approx. 30 Servings
 
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